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New Orleans Saints vs San Francisco 49ers | Best Bets and Betting Odds | NFL Week 12

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The San Francisco 49ers (6W-4L) will meet the New Orleans Saints (4W-7L) in Santa Clara on Sunday, November 27 at Levi’s Stadium. No doubt each of these teams will be searching for a win, so don’t forget to place your bets and then catch the excitement live at 1:25 PM PT!

For context surronding this game, let’s check to see how the 49ers and the Saints have performed versus each other historically. While the teams have battled in two contests over the past few years, the home team in this contest, the 49ers, have earned a win once against their opponents. In their most recent meeting on November 15, 2020, the end result was 27-13 in favor of the Saints.

Betting Preview for the New Orleans Saints vs San Francisco 49ers NFL Week 12 Game on November 27 2022

Where: Levi’s Stadium in Santa Clara, California

When: Sunday, November 27, 2022 at 1:25 PM PT

Betting on the New Orleans Saints

Regular Season Record: (4W-7L) | National Football Conference Standing: 13

The New Orleans Saints have experienced an assortment of victories and failures lately and are ready to move up in the standings when all is said and done. In their previous game on Sunday, November 20, the Saints outplayed the Los Angeles Rams 27-20. Do you think the story will be the same this week?

On the offensive side of the ball, the Saints are averaging 253.82 passing yards per game and 4.49 yards per rush attempt. With a turnover margin of 0.82, New Orleans has maintained an average of 26:22 in possession time this season.

Absences and Injuries

At this time, the Saints are without Marcus Davenport (Calf), Ethan Greenidge (Knee), J.t. Gray (Hamstring), Albert Huggins (Undisclosed), James Hurst (Concussion), Mark Ingram (Knee – MCL), Cameron Jordan (Orbital), Alvin Kamara (Illness), Jarvis Landry (Ankle), Marshon Lattimore (Abdomen), Erik McCoy (Calf), Andrus Peat (Triceps), Bradley Roby (Ankle), Dylan Soehner (Undisclosed), Michael Thomas (Toe), Payton Turner (Ankle), Pete Werner (Ankle), Forrest Lamp (Undisclosed), Sharif Finch (Undisclosed), Jerald Hawkins (Undisclosed), Trevor Penning (Toe), D’Marco Jackson (Undisclosed), Smoke Monday (Knee – ACL), Chase Hansen (Knee), and Brian Allen (Thumb).

Betting on the San Francisco 49ers

Regular Season Record: (6W-4L) | National Football Conference Standing: 3

The San Francisco 49ers have been eyeing what could be the start of a streak and are currently in 1st place in the NFC West. In their latest appearance on Monday, November 21, the 49ers defeated the Arizona Cardinals by a score of 10-38, and we can’t wait to see what happens when they meet the Saints in this Week 12 matchup.

So far this season, the 49ers are averaging 245.3 passing yards per game and 4.51 yards per rushing attempt. With an average possession time of 30:56, San Francisco is holding a turnover margin of -0.3.

Absences and Injuries

The 49ers will play without Arik Armstead (Foot), Samson Ebukam (Quadriceps), Maurice Hurst Jr. (Biceps), Javon Kinlaw (Knee), Trey Lance (Ankle), Jordan Matthews (Knee – ACL), Emmanuel Moseley (Knee – ACL), Deebo Samuel (Hamstring), Jason Verrett (Achilles), and Kalia Davis (Undisclosed).

New Orleans Saints vs San Francisco 49ers | Moneyline, Over/Under and Point Spread Odds

Moneyline Pick: San Francisco 49ers (-430) at FanDuel

The 49ers are considered the favorite. The team comes into the game with a winning percentage of 60%. Alternatively, the Saints’ winning percentage is 36%.

Over/Under Pick: Over 43 Points (-110) at FanDuel

The San Francisco 49ers have recorded an average of 23.6 points per game during the regular season. Meanwhile, the New Orleans Saints have logged 22.64 points.

Spread Pick: New Orleans Saints 8.5 Points (-110) at FanDuel

The New Orleans Saints will need to lose by less than the amount of the spread or win outright in order to cover.

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