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RB Leipzig vs Manchester City Predictions, Picks, and Betting Odds for Champions League Round of 16 | Feb 22 2023

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Manchester City's Jack Grealish, top, duels for the ball with Leipzig's Josko Gvardiol during the Group A Champion's League soccer match between RB Leipzig and Manchester City at the Red Bull Arena in Leipzig, Germany, Tuesday, Dec. 7, 2021. (AP Photo/Michael Sohn)

The Champions League Round of 16 has a very interesting game for soccer fans around the world, as RB Leipzig vs Manchester City will be facing each other next Wednesday. The German team came close to pulling off an upset in Group F by finishing second, just one point behind Real Madrid, while the English team qualified as undefeated Group G leaders.

It is worth remembering that the two teams met last campaign in the group stage of the Champions League, with one victory for each side. Without further ado, at JefeBet we bring you the best preview of the stellar match between RB Leipzig vs Manchester City.

Predictions, Odds, and Betting Preview for the RB Leipzig vs Manchester City Champions League Round of 16 on February 22, 2023

RB Leipzig vs Manchester City Prediction Picks Betting Odds Round of 16 First Leg Game on February 22, 2023
  • Where: Red Bull Arena – Leipzig, Germany.
  • When: Wednesday, February 22, 2:30 PM E.T.
  • Moneyline: RB Leipzig (+370) / Tie (+280) / Manchester City (-124).
  • Asian Handicap: RB Leipzig (+0.75, -118) / Manchester City (-0.75, -105).
  • Over/Under (2.5): Over (-143) / Under (+116)
  • Both teams score: Yes (-148) / No (+118).

All odds shown are courtesy of Unibet.

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Betting on RB Leipzig

RB Leipzig vs Manchester City Prediction Picks Betting Odds Round of 16 First Leg Game on February 22, 2023

In recent campaigns RB Leipzig have shown that they are quite a dangerous team in Europe and in this edition of the Champions League they have a great opportunity to pull off another upset. Of course, they will not be favorites to face Manchester City in the round of 16, but Marco Rose’s men have already beaten the English on this stage last year and in the Bundesliga they have come out on top against similar teams such as Bayern Munich and Borussia Dortmund.

In fact, in their home league they are fifth in the standings with 39 points, five points behind the three leaders Bayern, Dortmund and Union Berlin. Two weeks ago, Leipzig also ended an 18-game unbeaten run in official competitions.

In their campaign through the Champions League group stage, the Germans lost their first two games, conceding six goals, but they recovered by winning four in a row, including a game as locals against the mighty Real Madrid.

What’s more, in the Bundesliga, Leipzig have lost just one game in 10 matches, which came last week against Union Berlin. Likewise, they count on a good defense that has allowed only nine goals in front of its fans, while it is the third team with the least number of goals conceded in the domestic competition with only 26.

For this match, they have two notable absentees, defender Abdou Diallo and Spanish midfielder Dani Olmo.

Probable lineup (4-2-3-1): Janis Blaswich, Lukas Klostermann, Willi Orban, Josko Gvardiol, David Raum, Xaver Schlager, Amadou Haidara, Dominik Szoboszlai, Emil Forsberg, Timo Werner, André Silva.

Betting on Manchester City

RB Leipzig vs Manchester City Prediction Picks Betting Odds Round of 16 First Leg Game on February 22, 2023

One of the favorites to win the tournament this season begins its path through the final rounds facing a very difficult opponent and in not at all an encouraging moment. Although second in the Premier League, just two points behind Arsenal, Pep Guardiola’s team has not found consistency this year, as evidenced by their draw with Nottingham Forest just three days after beating the Gunners to equal them in first place.

That instability in their performance is what generates doubt on the Citizens’ chances of winning the Champions League title, despite finishing the group stage undefeated against teams like Borussia Dortmund and Sevilla.

Along with Bayern Munich, the English team was the team with the best defensive efficiency in the group stage with only two goals conceded, and in the Premier League it is the third club with the fewest goals conceded in the tournament with 24.

As for their away form, while City have not looked comfortable playing away from Manchester in the same manner. It is the second-best club on the road with 21 points from 12 games, while in the group stage, it ended with one win and two 0-0 draws.

Probable lineup (3-2-4-1): Ederson, Nathan Ake, Rúben Dias, Kyle Walker; Bernardo Silva, Rodri, Phil Foden, Kevin de Bruyne, Ilkay Gundogan, Jack Grealish, Erling Haaland.

JefeBet Prediction

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If Manchester City want to prove that they have what it takes to win the Champions League, getting a solid result on their visit to Germany is certainly a must. Guardiola’s side played two goalless draws away from home in the group stage, and Leipzig beat them 2-1 at home last campaign.

City’s own manager has commented that they have found it difficult to play away from home this year, although in their last 26 European matches their record on the road is 15 wins, six draws and five losses.

It should also be noted that both teams have good defenses, but Manchester have the best offense in the Premier League with 60 goals in 24 games, while Leipzig is the third-highest scoring team in the Bundesliga with 43.

Prediction: Over (LEI 2 – MCI 2).


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Written by Henry Roldán

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