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San Diego Padres vs San Francisco Giants Predictions, Picks, Odds, and Betting Preview | June 22 2023

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San Diego Padres' Ha-Seong Kim reacts after striking out against the San Francisco Giants during the second inning of a baseball game in San Francisco, Wednesday, June 21, 2023. (AP Photo/Jeff Chiu)

The San Francisco Giants beat the San Diego Padres Wednesday, 4-2. Will they be able to complete a sweep of San Diego? Or will the Padres be the ones to end San Francisco’s run?

Read on for more about this Padres vs Giants matchup in the 2023 MLB regular season, including our predictions, picks, and latest odds to win this showdown, as brought to you by JefeBet. Also, don’t forget to check out the other MLB game previews here to help you make the best betting decisions.

Predictions, Odds, and Betting Preview for the San Diego Padres vs San Francisco Giants  MLB Regular Season Game on June 22, 2023

Padres vs Giants Picks Odds MLB June 22 2023
  • Where: Oracle Park, San Francisco, California
  • When: Thursday, June 22, 2023, 3:45 PM ET
  • Where to Watch: MLB.tv
  • Moneyline: San Diego Padres (-130) vs San Francisco Giants (+110)
  • Over/Under: 8.5

All odds are provided by DraftKings.

Betting on the San Diego Padres (-130)

Padres vs Giants Picks Odds MLB June 22 2023

The Padres will have one more crack at a win in this series, and they will have Blake Snell on the mound to help them get to that goal. Snell is coming off a sterling performance, as he allowed zero earned runs on two hits in six innings of a 2-0 victory over the majors-leading Tampa Bay Rays last Saturday at home. 

He also had 12 strikeouts against the Rays – his second start in a row with as many punchouts. Snell has been incredible of late, having surrendered just an earned run over his last four starts that stretched 25 innings. San Diego is 4-0 in its last Game 3s of a series. Also, the Padres are 7-3 in their last 10 games after a loss. Manny Machado will come into this game hoping to add to his success when up against Alex Wood. He is 4-for-13 with two walks against Wood in his career.

Starting pitcher: Blake Snell (3-6, 3.48 ERA)

MLB
CHOOSE ONE:
San Diego Padres: -130
San Francisco Giants: +110
Tie:

 

 
* Odds subject to change

Betting on the San Francisco Giants (+110)

Padres vs Giants Picks Odds MLB June 22 2023

San Francisco is on fire. The Giants now have a 10-game win streak going for them after their win over the Padres Wednesday night. However, star outfielder Mike Yastrzemski suffered an injury that might cause him to miss Thursday’s contest. Still, the like of Joc Pederson

and JD Davis can provide a lift for the Giants, who will give Alex Wood the starting duties. 

Wood was fantastic in his first start after over two weeks of absence. Against the Dodgers last Saturday, Wood held his former team to zero runs on three hits allowed with four strikeouts in a 15-0 victory on the road.  The Giants have won in four of his last five starts.  Pederson hit .311 with three home runs and 10 RBI in his last 13 games while Davis batted .286 with a home run and seven RBI in the same stretch.

Starting pitcher: Alex Wood (2-1, 4.11 ERA)

El Jefe’s Prediction on San Diego Padres vs San Francisco Giants

The Giants are on a roll, but they’re also banged up. Blake Snell will have the Padres snapping San Francisco’s win streak.

Prediction: 

The Padres win, 3-2.

Bet on the Padres here

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