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San Diego Padres vs Arizona Diamondbacks Predictions, Picks, Odds, and Betting Preview | Apr 21 2023

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San Diego Padres' Manny Machado batting during a baseball game against the Milwaukee Brewers Sunday, April 16, 2023, in San Diego. (AP Photo/Brandon Sloter)

The 2023 MLB season continues with another exciting match-up, the Padres vs Diamondbacks, on Friday, April 21st. Both teams are looking to make a mark in the National League West division.

Stay up-to-date with all the information and odds for the 2023 baseball season at JefeBet. Here’s everything you need to know about this thrilling game between the San Diego Padres vs Arizona Diamondbacks.

Predictions and Betting Preview for the Padres vs Diamondbacks MLB Regular Season Game on April 21, 2023

Padres vs Diamondbacks predictions picks betting odds for the game on April 21, 2023
  • Where: Chase Field, Phoenix, Arizona
  • When: Friday, April 21, 2023, 9:40 PM ET


Betting on the San Diego Padres

Padres vs Diamondbacks predictions picks betting odds for the game on April 21, 2023
  • Regular Season Record: 9-11

The Padres haven’t been able to show the impressive level expected of them so far, and the most surprising thing is that their offense is struggling to score runs despite having Juan Soto, Manny Machado, and Xander Bogaerts in the middle of the lineup.

San Diego has the third-worst collective batting average in MLB at .223, something that nobody could have imagined. It’s too early in the season to hit the panic button, but the offense definitely needs to start performing better. This is a team that made a huge investment to reach the World Series, and anything less than that will be considered an absolute failure.

One good news is that pitcher Joe Musgrove has recovered from his foot injury and will make his season debut in 2023 in Arizona.

Starting Pitcher: Seth Lugo (2-0, 2.70 ERA)

Betting on the Arizona Diamondbacks

Padres vs Diamondbacks predictions picks betting odds for the game on April 21, 2023
  • Regular Season Record: 11-8

The Arizona Diamondbacks have taken advantage of the Dodgers’ and Padres’ inconsistent start to the season, placing themselves in first place in the National League West Division. It’s worth noting that many analysts predicted this team to be one of the breakout teams of 2023, and so far they have lived up to those expectations.

What’s most surprising is that Arizona has managed to have a strong start to the season despite their pitching not performing well. The team’s collective ERA is 4.96, which ranks them 22nd in that category.

The offense has been strong, with the team’s 165 hits ranking them ninth in the MLB. They are also second in doubles with a total of 44, just one behind the 45 held by the Philadelphia Phillies.

Starting Pitcher: Zac Gallen (2-1, 3.33 ERA)



JefeBet Prediction

The Padres have won 15 of their last 20 matchups against the Diamondbacks, but it will be a tough task to repeat that dominance against a top-notch pitcher like Zac Gallen. So, for this Padres vs Diamondbacks game, at JefeBet, we believe Arizona will come out on top in a closely contested game.

Prediction: Arizona Diamondbacks Runline (SD 3-4 ARI)


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