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Buffalo Bills vs Detroit Lions Predictions, Picks, Odds, and Betting Preview | NFL Week 12 2022

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Buffalo Bills offensive tackle Cody Ford (74) blocks for quarterback Davis Webb, right, against Detroit Lions defensive tackle Brian Price (76) during the first half of a preseason NFL football game, Friday, Aug. 13, 2021, in Detroit. (AP Photo/Duane Burleson)

The NFL’s Week 12 will begin with a special matchday on Thanksgiving Day this year, when, per league tradition, a total of three games will be played from midday to night for the entertainment of all football fans. The curtain raiser will be Bills vs Lions.

While the home club will want to build on its strong November performance, the visiting squad is aware that it must continue to add up victories in a division that is extremely competitive. Today, at JefeBet we bring you our predictions for the Buffalo Bills vs Detroit Lions match, along withsome of the best odds for the event.

Predictions and Betting Preview for the Buffalo Bills vs Detroit Lions NFL Week 12 Game on November 24, 2022

Bills vs Lions Predictions Picks Betting Odds
  • Where: Ford Field, Detroit, Michigan.
  • When: Thursday, November 24, 12:30 PM E.T.

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Betting on the Buffalo Bills

Bills vs Lions Predictions Picks Betting Odds
  • Season record: 7-3
  • BetMGM Spread: -9.5
  • BetMGM Moneyline: -455
  • Over/Under: 54.5

The Buffalo Bills were the clear favorites to win the Super Bowl at the start of the season, and they still hold that title after a strong campaign. However, the team is aware that it must keep winning if it wants to advance past the regular season in the competitive American Conference East division.

Only one game separates Bills, Dolphins, Patriots and Jets in the standings, so the week-to-week results could totally change the outlook. In this way, Buffalo will want to keep on adding victories after winning its last game, 31-23, against the Cleveland Browns, thus breaking a streak of two consecutive defeats.

However, the Bills have now allowed 20 or more points in three consecutive games;moreover, the team’s defense will be key, and they’ll hope that their offense continues to perform as it has done so this season, being the second best in total yards per game average (427.3), points average (28.1) and third-chance conversion percentage (50.0%).

Betting on the Detroit Lions

Bills vs Lions Predictions Picks Betting Odds
  • Regular Season Record: 4-6
  • Unibet Spread: +9.5
  • Unibet Moneyline: 360
  • Over/Under: 54.5

The Minnesota Vikings rule the North Division with an iron fist, while the Detroit Lions, unlike their opponent, are in the division with the most disparate teams in the National Conference. As a result of a three-game winning streak that helped them leave the bottom of the standings, they are currently in second place.

The most remarkable aspect of this victory is that two of those wins happened against divisional rivals the Green Bay Packers (15-9) and the Chicago Bears (31-30); meanwhile, in the previous week they outperformed the New York Giants (31-18), which will fill them with confidence for this match against an important opponent.

Good offense has been one of the keys for Detroit this season, with the team averaging 25.0 points per game (eighth-best average in the league), while averaging the seventh-most total yards per game (377.6).

JefeBet Prediction

Beyond the Detroit Lions’ good offense, it is impossible to overlook that they are the worst team in the NFL defensively.They are last in average total yards allowed per game (427.3), average points allowed (28.2) and opponents’ third-down conversion percentage (50.0%), and second to last in average rushing yards allowed (153.7).

All of this will work like a charm for the Bills, who can quietly exploit all of these weaknesses with a great offense. However, it remains to be seen if Buffalo can improve on the weaknesses they have shown on defense recently, especially in this visit to Ford Field.

Detroit has scored 30 or more points in three of its five home games this season,but they also allowed more than 30 points in three of those games, which leads us to believe that this Thanksgiving Day will start with a very lively game and that it will have a high score.

Prediction: Over (BUF 31 – DET 26)

Betting odds courtesy of BetMGM and Unibet. Don’t miss out on our reviews!


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Written by Hiram Moreno

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