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Predictions, Odds, and Betting Preview for the NCAA Football Week 6 Season 2022

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The Clemson band performs before an NCAA college football game against North Carolina State Saturday, Oct. 1, 2022, in Clemson, S.C. (AP Photo/Jacob Kupferman)

Week 5 has now passed, which means we have officially reached the halfway point of the college football regular season, and this NCAA Football Week 6 promises to mark the way for multiple teams heading into the end of the season.

The day is scheduled to begin next Thursday, October 6, with multiple matches being played as usual on Saturday, on Sunday, and on Monday. So, at JefeBet, we give you an overview of the games the teams ranked in the AP Top 25 will play in this NCAA Football Week 6 in case you want to bet on them.

All odds shown below are courtesy of Unibet.

Predictions, Odds, and Betting Preview for NCAA Football Week 6 Matchups

Arkansas Razorbacks vs Mississippi State Bulldogs / Saturday, October 8 / 12:00 PM E.T.

NCAA Football Week 6 2022 Predictions Odds Betting Preview
  • Arkansas Moneyline: +240
  • Mississippi State Moneyline: -315
  • Arkansas Spread: +8
  • Mississippi State Spread: -8
  • Over/Under: 62.0

Prediction: Mississippi State Spread

[NCAA Football Week 6 Arkansas vs Mississippi State full betting preview here]

Michigan Wolverines vs Indiana Hoosiers / Saturday, October 8 / 12:00 PM E.T.

NCAA Football Week 6 Season 2022 Predictions Odds Betting Preview
  • Michigan Moneyline: -2500
  • Indiana Moneyline: +950
  • Michigan Spread: -22
  • Indiana Spread: +22
  • Over/Under: 59.0

Prediction: Over

[NCAA Football Week 6 Michigan vs Indiana complete betting preview soon]

TCU Horned Frogs vs Kansas Jayhawks / Saturday, October 8 / 12:00 PM E.T.

NCAA Football Week 6 Season 2022 Predictions Odds Betting Preview
  • TCU Moneyline: -275
  • Kansas Moneyline: +210
  • TCU Spread: -7
  • Kansas Spread: +7
  • Over/Under: 67.5

Prediction: Kansas Spread

[NCAA Football Week 6 TCU vs Kansas complete betting preview soon]

LSU Tigers vs Tennessee Volunteers / Saturday, October 8 / 12:00 PM E.T.

NCAA Football Week 6 Season 2022 Predictions Odds Betting Preview
  • LSU Moneyline: +116
  • Tennessee Moneyline: -148
  • LSU Spread: +2.5
  • Tennessee Spread: -2.5
  • Over/Under: 64.0

Prediction: Under

[NCAA Football Week 6 LSU vs Tennessee full betting preview here]

South Florida Bulls vs Cincinnati Bearcats / Saturday, October 8 / 2:30 PM E.T.

NCAA Football Week 6 Season 2022 Predictions Odds Betting Preview
  • South Florida Moneyline: N/A
  • Cincinnati Moneyline: N/A
  • South Florida Spread: +27.5
  • Cincinnati Spread: -27.5
  • Over/Under: 59.0

Prediction: Cincinnati Spread

[NCAA Football Week 6 South Florida vs Cincinnati complete betting preview soon]

Texas Tech Red Raiders vs Oklahoma State Cowboys / Saturday, October 8 / 3:30 PM E.T.

NCAA Football Week 6 Season 2022 Predictions Odds Betting Preview
  • Texas Tech Moneyline: +250
  • Oklahoma State Moneyline: -345
  • Texas Tech Spread: +9
  • Oklahoma State Spread: -9
  • Over/Under: 67.5

Prediction: Over

[NCAA Football Week 6 Texas vs Oklahoma complete betting preview here]

Utah Utes vs UCLA Bruins / Saturday, October 8 / 3:30 PM E.T.

NCAA Football Week 6 Season 2022 Predictions Odds Betting Preview
  • Utah Moneyline: -200
  • UCLA Moneyline: +155
  • Utah Spread: -4.5
  • UCLA Spread: +4.5
  • Over/Under: 64.5

Prediction: Under

[NCAA Football Week 6 Utah vs UCLA full betting preview here]

Auburn Tigers vs Georgia Bulldogs / Saturday, October 8 / 3:30 PM E.T.

NCAA Football Week 6 Season 2022 Predictions Odds Betting Preview
  • Auburn Moneyline: N/A
  • Georgia Moneyline: N/A
  • Auburn Spread: +29
  • Georgia Spread: -29
  • Over/Under: 50.0

Prediction: Georgia Spread

[NCAA Football Week 6 Auburn vs Georgia complete betting preview soon]

Ole Miss Rebels vs Vanderbilt Commodores / Saturday, October 8 / 4:00 PM E.T.

NCAA Football Week 6 Season 2022 Predictions Odds Betting Preview
  • Ole Miss Moneyline: -1115
  • Vanderbilt Moneyline: +650
  • Ole Miss Spread: -19
  • Vanderbilt Spread: +19
  • Over/Under: 59.5 Points

Prediction: Under

[NCAA Football Week 6 Ole Miss vs Vanderbilt complete betting preview here]

Washington Huskies vs Arizona State Sun Devils / Saturday, October 8 / 4:00 PM E.T.

NCAA Football Week 6 Season 2022 Predictions Odds Betting Preview
  • Washington Moneyline: -560
  • Arizona State Moneyline: +390
  • Washington Spread: -13.5
  • Arizona State Spread: +13.5
  • Over/Under: 58.5

Prediction: Under

[NCAA Football Week 6 Washington vs Arizona complete betting preview soon]

Ohio State Buckeyes vs Michigan State Spartans / Saturday, October 8 / 4:00 PM E.T.

NCAA Football Week 6 Season 2022 Predictions Odds Betting Preview
  • Ohio State Moneyline: -10000
  • Michigan State Moneyline: +1500
  • Ohio State Spread: -25.5
  • Michigan State Spread: +25.5
  • Over/Under: 63.0

Prediction: Ohio State Spread

[NCAA Football Week 6 Ohio vs Michigan State complete betting preview soon]

Washington State Cougars vs USC Trojans / Saturday, October 8 / 7:30 PM E.T.

NCAA Football Week 6 Season 2022 Predictions Odds Betting Preview
  • Washington State Moneyline: -530
  • USC Moneyline: +360
  • Washington State Spread: +13
  • USC Spread: -13
  • Over/Under: 50.0

Prediction: Under

[NCAA Football Week 6 Washington State vs USC complete betting preview soon]

BYU Cougars vs Notre Dame Fighting Irish / Saturday, October 8 / 7:30 PM E.T.

NCAA Football Week 6 Season 2022 Predictions Odds Betting Preview
  • BYU Moneyline: -177
  • Notre Dame Moneyline: +132
  • BYU Spread: -3.5
  • Notre Dame Spread: +3.5
  • Over/Under: 52.0

Prediction: Notre Dame Spread

[NCAA Football Week 6 BYU vs Notre Dame full betting preview here]

Kansas State Wildcats vs Iowa State Cyclones / Saturday, October 8 / 7:30 PM E.T.

NCAA Football Week 6 Season 2022 Predictions Odds Betting Preview
  • Kansas State Moneyline: -134
  • Iowa State Moneyline: +106
  • Kansas State Spread: -2
  • Iowa State Spread: +2
  • Over/Under: 45.5

Prediction: Under

[NCAA Football Week 6 Kansas State vs Iowa State complete betting preview soon]

Clemson Tigers vs Boston College Eagles / Saturday, October 8 / 7:30 PM E.T.

NCAA Football Week 6 Season 2022 Predictions Odds Betting Preview
  • Clemson Moneyline: -1667
  • Boston College Moneyline: +850
  • Clemson Spread: -20
  • Boston College Spread: +20
  • Over/Under: 50.0

Prediction: Clemson Spread

[NCAA Football Week 6 Clemson vs Boston College complete betting preview soon]

South Carolina Gamecocks vs Kentucky Wildcats / Saturday, October 8 / 7:30 PM E.T.

NCAA Football Week 6 Season 2022 Predictions Odds Betting Preview
  • South Carolina Moneyline: +320
  • Kentucky Moneyline: -435
  • South Carolina Spread: +10.5
  • Kentucky Spread: -10.5
  • Over/Under: 49.5

Prediction: Over

[NCAA Football Week 6 South Carolina vs Kentucky full betting preview here]

Army Black Knights vs Wake Forest Demon Deacons / Saturday, October 8 / 7:30 PM E.T.

NCAA Football Week 6 Season 2022 Predictions Odds Betting Preview
  • Army Moneyline: +480
  • Wake Forest Moneyline: -715
  • Army Spread: +17
  • Wake Forest Spread: -17
  • Over/Under: 67.5

Prediction: Wake Forest Spread

[NCAA Football Week 6 Army vs Wake Forest complete betting preview soon]

Texas A&M Aggies vs Alabama Crimson Tide / Saturday, October 8 / 8:00 PM E.T.

NCAA Football Week 6 Season 2022 Predictions Odds Betting Preview
  • Texas A&M Moneyline: +1300
  • Alabama Moneyline: -5000
  • Texas A&M Spread: +24
  • Alabama Spread: -24
  • Over/Under: 51.0

Prediction: Over

[NCAA Football Week 6 Texas A&M vs Alabama complete betting preview soon]

Florida State Seminoles vs NC State Wolfpack / Saturday, October 8 / 8:00 PM E.T.

NCAA Football Week 6 Season 2022 Predictions Odds Betting Preview
  • Florida State Moneyline: +123
  • NC State Moneyline: -159
  • Florida State Spread: +3
  • NC State Spread: -3
  • Over/Under: 52.0

Prediction: Under

[NCAA Football Week 6 Florida State vs NC State full betting preview here]

Oregon Ducks vs Arizona Wildcats / Saturday, October 8 / 9:00 PM E.T.

NCAA Football Week 6 Season 2022 Predictions Odds Betting Preview
  • Oregon Moneyline: -530
  • Arizona Moneyline: +360
  • Oregon Spread: -13
  • Arizona Spread: +13
  • Over/Under: 70.0

Prediction: Over

[NCAA Football Week 6 Oregon vs Arizona full betting preview here]


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Written by Hiram Moreno

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