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MLS Matchday 22 Predictions, Picks, and Betting Odds

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Foto: Cortesía Twitter @HoustonDynamo

The twenty-second matchday of the Major League Soccer will take place on the first weekend of July, with 14 thrilling matches. While awaiting the arrival of Lionel Messi, 28 franchises will be looking to rack up important points with the Playoffs on the horizon.

If you want to place a bet on any of these games, JefeBet brings you the best preview of this upcoming matchday in the MLS. Keep on reading to have access to our predictions, the best available betting odds brought by our affiliates, and the latest information for you to bet well-informed. What’s more, don’t forget to take advantage of the great welcome bonus offered by Codere, our odds provider for this exciting matchday.






Predictions, Odds, and Betting Preview for MLS Matchday 22

FC Cincinnati (+110) vs New England Revolution (+240) | Saturday, July 1 | 7:30 PM E.T.

MLS Matchday 21 Predictions Picks Betting Odds
Photo courtesy of @fccincinnati on Twitter
  • FC Cincinnati Asian Handicap: -1
  • New England Revolution Asian Handicap: +1
  • Over/Under: 2.5

The two top teams in the Eastern Conference are set to clash next Saturday. It seemed like FC Cincinnati was on track to finally defeat their long-time rival after six losses and two draws since 2019. However, their devastating 0-3 loss to DC United in their previous match has left more uncertainties for what lies ahead.

This was only the second stumble for the home team, affectionately known as the Orange and Blue, in the domestic tournament where they currently sit atop their division with 43 points. With 13 victories under their belt, they have found the back of the net three times in five of those wins.

Their opponent is another team that excels in the attacking department, as evidenced by their recent tally of eight goals in their last three matches. It’s worth noting that the visiting team has managed to score in all of their previous FC Cincinnati vs New England Revolution encounters, and the home team has done the same in 83.3% of those matches.

Codere is offering an enticing line of (-176) for Both Teams to Score: Yes, with the potential to win up to $100 for every $175 wagered.

Prediction: Both Teams Score: Yes and Over (CIN 2-3 NER)

FC Dallas (+180) vs Los Angeles FC (+145) | Saturday, July 1 | 8:30 PM E.T.

MLS Matchday 21 Predictions Picks Betting Odds
Photo: Courtesy Twitter @LAFC
  • FC Dallas Asian Handicap: -0.5
  • Los Angeles FC Asian Handicap FC: +0.5
  • Over/Under: 2.5

The runner-up in the Western Conference will take on the seventh-place team in a decisive match with major implications for the future. They are only separated by six points, and both teams are coming off losses, conceding three goals in their last game.

At the Toyota Stadium in Texas, FC Dallas has secured three points in five out of their nine matches, while their competitor has only managed to win three times away from home. It’s worth noting that the home team has scored 14 out of their 21 goals in front of their home crowd, while Los Angeles FC has only netted 10 out of their 28 on the road.

However, the visiting team has the advantage in their head-to-head encounters, winning four out of the last five match-ups and scoring at least two goals in each of those victories.

Taking all these factors into consideration, if you want to bet that the Over (3.5) will be covered, Codere is offering odds of (+225), which could potentially win you $225 for every $100 wagered. .

Prediction: Los Angeles FC Moneyline and Over (DAL 2-3 LAFC).

Seattle Sounders (-125) vs Houston Dynamo (+330) | Saturday, July 1 | 10:30 PM E.T.

MLS Matchday 21 Predictions Picks Betting Odds
Photo courtesy Twitter @SoundersFC.
  • Seattle Sounders Asian Handicap: -1
  • Houston Dynamo Asian Handicap: +1
  • Over/Under: 2.5

Third against fourth in the Western Conference will go head-to-head at the Lumen Field. The visitors know that a victory could leapfrog them over the home team, but they’ll have to step it up big time, as they have succumbed in seven out of their last 10 away games.

Luckily for them, they’ll be up against a team that has only managed to rack up five out of the last 15 points at their stadium, with just one win and two draws. What’s really worrisome for the home team is that those two draws were goalless. And get this, they’ve only conceded five goals at home so far this season.

If you agree with us and think the same pattern will repeat itself, head over to Codere and bet on the Under (2.5), which has odds of (-121) that could earn you up to $83 for every $100 you wager.

Prediction: Tie and Under (SEA 1-1 HOU).

Atlanta United (+135) vs Philadelphia Union (+190) | Sunday, July 2 | 4:00 PM E.T.

MLS Matchday 21 Predictions Picks Betting Odds
Photo: Courtesy of @ATLUTD on Twitter
  • Asian Handicap Atlanta United: -0.5
  • Asian Handicap Philadelphia Union: +0.5
  • Over/Under: 3.5

Atlanta United vs Philadelphia Union is the game that will conclude this twenty-second matchday next Sunday. The sixth-placed team in the East will host their fourth-placed counterparts with the sole objective of closing the gap to just two points in the standings.

These two teams are among the top three highest-scoring clubs in their division, with 37 and 34 goals respectively, only trailing behind Columbus Crew (38). What’s more, The Five Stripes have scored 24 out of those 37 goals in just 10 home games, averaging over two goals per game at home.

If there were any doubts about this being an action-packed clash, the Zolos will put them to rest when you find out that their last five away games have had at least three goals.

If you want to take advantage of this information and bet on the Over (3.5), Codere offers odds of (+170), which could earn you $170 for every $100 you wager.

Prediction: Atlanta United Moneyline and Over (ATL 2-1 PHI).

Other MLS Matchday 22 Games

MLS Matchday 21 Predictions Picks Betting Odds
Photo: Courtesy Twitter @NYCFC

Toronto FC(+105) vs Real Salt Lake (+235), Saturday, July 1 7:30 PM E.T.

  • Prediction: Over (TOR 1-2 RSL).

Orlando City (-121) vs Chicago Fire (+310), Saturday, July 1 7:30 PM E.T.

  • Prediction: Draw (ORL 1-1 CHI).

CF Montreal (+130) vs New York City FC (+200), Saturday July 1 7:30 PM E.T.

  • Prediction: Both Teams Score: No (MON 1-0 NYC).

Columbus Crew (+100) vs New York Red Bulls (+280), Saturday, July 1 7:30 PM E.T.

  • Prediction: Over (COL 3-1 NYR).

Inter Miami(+145) vs. Austin FC (+175), Saturday, July 1 7:30 PM E.T.

  • Prediction: Austin Moneyline (AUS 2-1 INT).

Nashville SC (-114) vs DC United (+290), Saturday, July 1 8:30 PM E.T.

  • Prediction: Moneyline DC United and Over (NAS 1-3 DCU).

St Louis City FC. (-114) vs Colorado Rapids (+290), Saturday, July 1 8:30 PM E.T.

  • Prediction: Over (STL 4-1 COL).

Minnesota United (+115) vs Portland Timbers (+225), Saturday, July 1 8:30 PM E.T.

  • Prediction: Draw (MIN 1-1 POR).

Sporting KC (-106) vs Vancouver Whitecaps (+260), Saturday, July 1 8:30 PM E.T.

  • Prediction: Under (SKC 1-1 VAN).

San Jose Earthquakes (+105) vs Los Angeles Galaxy (+225), Saturday, July 1 10:30 PM E.T.

  • Prediction: Draw (SJE 1-1 LAG).

Bet on any of these matches here.


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