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San Francisco Giants vs Chicago Cubs Best Bets and Betting Odds | Sep 11 2022

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On Sunday, September 11, the San Francisco Giants (66-73) will square off against the Chicago Cubs (58-81) at Wrigley Field in Chicago for a regular season matchup. As we make our way through the home stretch of this regular season, each of these teams will surely be vying to come out on top in this head-to-head matchup. Get your picks in and catch the action when it all goes down at 7:08 PM CT!

Take a peek at how Chicago and San Francisco have fared against each other historically for context related to Sunday’s regular season matchup.

So far this season, these ball clubs have battled in seven contests, and the Cubs have earned a win three times against their opponents. When they last met on on Saturday, the Chicago Cubs came out on top by a score of 2-5. The Cubs had two runs and seven hits, whereas the Giants racked up five runs on 11 hits. We’ll see what plays out this time when these two teams square off at Wrigley Field.

Betting Preview for the San Francisco Giants vs Chicago Cubs MLB Game on September 11 2022

Where: Wrigley Field in Chicago, IL

When: Sunday, September 11, 2022 at 7:08 PM CT

Betting on the San Francisco Giants

Record: (66W-73L) | National League West Standing: 3

The Giants lost to the Chicago Cubs 2-5 in their most recent outing on Saturday, and we’ll be interested to see if this momentum continues. Overall this season, the Giants are currently batting .234 thanks in large part to their top hitter, Joc Pederson, who has a batting average of .270. Defensively, they carry an ERA of 3.9 and a .984 fielding percentage. Before you place your bet, don’t forget to review our odds assessment below!

Absences and Injuries

Per the latest inactive report, the Giants will play without Robert Wynns (Head), Gregory Santos (Groin), Brandon Belt (Knee), Donovan Walton (Shoulder), Austin Slater (Hand), Robert Wood (Shoulder), José Álvarez (Elbow), Mauricio Llovera (Hip), Colton Welker (Shoulder), Samuel Long (Oblique), Samuel Delaplane (Forearm), and Anthony DeSclafani (Ankle).

Betting on the Chicago Cubs

Record: (58W-81L) | National League Central Standing: 3

In their previous game on Saturday, the Cubs defeated the San Francisco Giants by a score of 2-5. Overall this season, the Cubs are currently batting .239 due in large part to their top bat, Nicholas Hoerner, who leads the team with a batting average of .285. In terms of defense, they have an ERA of 4.3 and a .984 fielding percentage. Make sure you check out our odds analysis below before selecting your picks!

Absences and Injuries

It’s confirmed that the Cubs are without Kyle Hendricks (Shoulder), Nicklaus Madrigal (Groin), Bradley Wieck (Elbow), Codi Heuer (Elbow), Nelson Velázquez (Illness), Steven Brault (Shoulder), Keegan Thompson (Back), Willson Contreras (Foot), Justin Steele (Undisclosed), Adbert Alzolay (Shoulder), Alec Mills (Back), Ethan Roberts (Shoulder), and Jason Heyward (Knee).

San Francisco Giants vs Chicago Cubs | Moneyline, Over/Under and Point Spread Odds

Moneyline Pick: Chicago Cubs (-110) at FanDuel

The Cubs are considered the favorite in this regular season showdown. The club could be having a more efficient start to September as they sport a winning percentage of 20% in the last 10 games (two victories and eight losses) they’ve played. On the other hand, the Giants’ winning percentage is greater at 50% in the last 10 games (five victories and five losses).

Over/Under Pick: Under 9 Total Runs (-120) at DraftKings

In this game, we are predicting that the combined total number of runs scored for both teams will be under 9. Don’t forget it while placing your bet!

Runline Pick: San Francisco Giants -1.5 Runs (+150) at DraftKings

The San Francisco Giants will need to win by the amount of the spread or more in order to cover a runline of -1.5.

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