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San Francisco Giants vs Colorado Rockies Best Bets and Betting Odds | Sep 21 2022

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The Colorado Rockies (64-83) will once again host the San Francisco Giants (70-77) on Wednesday, September 21 at Coors Field in Denver. As we make our way through the home stretch of this regular season, each of these teams will surely be battling for a victory in this head-to-head matchup. Be sure to catch the action at 6:40 PM MT!

Let’s explore how Colorado and San Francisco have played against each other in the past for background related to Wednesday’s regular season matchup.

So far this season, these ball clubs have battled in 10 contests, and the Rockies have earned a win five times against their opponents. In their last meeting on Tuesday, the Colorado Rockies came out on top to the tune of 3-6. The Rockies had seven runs and 16 hits, whereas the Giants racked up 10 runs on 15 hits. We’ll see who comes out victorious this time when these two teams go head to head at Coors Field.

Betting Preview for the San Francisco Giants vs Colorado Rockies MLB Game on September 21 2022

Where: Coors Field in Denver, CO

When: Wednesday, September 21, 2022 at 6:40 PM MT

Betting on the San Francisco Giants

Record: (71W-77L) | National League West Standing: 3

The Giants lost to the Colorado Rockies 7-10 in their most recent outing on Monday, and we’ll be interested to see if this momentum continues. Overall this season, the Giants are currently batting .233 thanks in large part to their hottest bat, Thairo Estrada, who is leading the squad with a batting average of .271. Defensively, they carry an ERA of 3.88 and a .983 fielding percentage. Prior to placing your bet, don’t forget to consult our odds assessment below!

Absences and Injuries

Per the latest inactive report, the Giants will play without Gregory Santos (Groin), Carlos Rodón (Hand), Brandon Belt (Knee), Donovan Walton (Shoulder), Robert Wood (Shoulder), José Álvarez (Elbow), Thomas La Stella (Neck), Mauricio Llovera (Hip), Colton Welker (Shoulder), Samuel Long (Oblique), Samuel Delaplane (Forearm), and Anthony DeSclafani (Ankle).

Betting on the Colorado Rockies

Record: (64W-84L) | National League West Standing: 5

In their previous game on Monday, the Rockies outplayed the San Francisco Giants by a score of 7-10. Overall this season, the Rockies are currently batting .257 due in large part to their top bat, Randal Grichuk, who is riding high with a batting average of .272. In terms of defense, they have an ERA of 5.03 and a .983 fielding percentage. Make sure you review our odds analysis further down before selecting your picks!

Absences and Injuries

Per the list of injuries and inactive players the Rockies are without Antonio Senzatela (ACL), Scott Oberg (Arm), Brendan Rodgers (Hamstring), José Iglesias (Hand), Kristopher Bryant (Foot), Lucas Gilbreath (Elbow), Tyler Kinley (Elbow), Helcris Olivarez (Shoulder), and Ryan Rolison (Shoulder).

San Francisco Giants vs Colorado Rockies | Moneyline, Over/Under and Point Spread Odds

Moneyline Pick: San Francisco Giants (-136) at FanDuel

The Giants are considered the favorite in this regular season showdown. The club comes into the game as they sport a winning percentage of 55.56% for this month, accounting a total of 10 wins. they’ve played. In comparison, the Rockies’ winning percentage is lower at 47.06% for this month, a record of eight victories in total.

Over/Under Pick: Under 9.5 Total Runs (-114) at FanDuel

In this game, we predict that the combined total number of runs scored for both teams will be under 9.5. Don’t forget it while placing your bet!

Runline Pick: San Francisco Giants -1.5 Runs (+112) at FanDuel

With a runline of -1.5, the San Francisco Giants will need to win by the amount of the spread or more in order to cover.

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