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San Francisco Giants vs San Diego Padres Best Bets and Betting Odds | Oct 5 2022

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On Wednesday, October 5, the San Francisco Giants (80-80) will go up against the San Diego Padres (88-72) at PETCO Park in San Diego for a regular season matchup. Moving along through the final third of the season, both teams will surely be searching for a victory in this showdown. Get your picks in and catch the action when it all goes down at 1:10 PM PT!

Let’s explore how San Diego and San Francisco have fared against each other historically for context about Wednesday’s regular season contest.

So far this season, these ball clubs have played in 10 matchups, and the Padres have earned a win seven times against their opponents. In their previous meeting on Monday, the San Diego Padres came out on top to the tune of 7-4. The Padres had seven runs and eight hits, whereas the Giants put up four runs on five hits. We’ll see what unfolds this time when these two teams square off at PETCO Park.

Betting Preview for the San Francisco Giants vs San Diego Padres MLB Game on October 5 2022

Where: PETCO Park in San Diego, CA

When: Wednesday, October 5, 2022 at 1:10 PM PT

Betting on the San Francisco Giants

Record: (80W-80L) | National League West Standing: 3

The Giants were defeated by the San Diego Padres 7-4 in their most recent outing on Monday, and we can’t wait to find out if they can come away victorious in this one. Overall this season, the Giants are currently batting .235 thanks in large part to their hottest bat, Joc Pederson, who is leading the squad with a batting average of .276. In terms of defense, they have an ERA of 3.85 and a .984 fielding percentage. Before you place your bet, don’t forget to review our evaluation of the odds below!

Absences and Injuries

Regarding inactive players, the Giants are missing Gregory Santos (Groin), Logan Webb (Undisclosed), Brandon Belt (Knee), Donovan Walton (Shoulder), Robert Wood (Shoulder), Evan Longoria (Thumb), José Álvarez (Elbow), Thomas La Stella (Neck), Mauricio Llovera (Hip), Thomas Szapucki (Hip), Colton Welker (Shoulder), Samuel Long (Oblique), Samuel Delaplane (Forearm), Anthony DeSclafani (Ankle), and Luis González (Back).

Betting on the San Diego Padres

Record: (88W-72L) | National League West Standing: 2

In their most recent game on Monday, the Padres beat the San Francisco Giants by a score of 7-4. Overall this season, the Padres are currently batting .240 due in large part to their top hitter, Manuel Machado, who has a batting average of .296. Defensively, they carry an ERA of 3.8 and a .987 fielding percentage. Be sure to explore our odds assessment further down before selecting your picks!

Absences and Injuries

It’s confirmed that the Padres will play without Thomas Pomeranz (Elbow) and Austin Adams (Forearm).

San Francisco Giants vs San Diego Padres | Moneyline, Over/Under and Point Spread Odds

Moneyline Pick: San Diego Padres (-148) at FanDuel

The Padres are considered the favorite in this regular season tiltball game. The club comes into the matchup as they sport a winning percentage of 50% in the last 10 games (five victories and five losses) they’ve played. On the other side of things, the Giants’ winning percentage is higher at 70% in the last 10 games (seven victories and three losses).

Over/Under Pick: Under 7.5 Total Runs (-118) at FanDuel

In this game, we predict that the combined total number of runs scored for both teams will be under 7.5. Don’t forget it while placing your bet!

Runline Pick: San Diego Padres -1.5 Runs (+138) at FanDuel

The San Diego Padres will need to win by the amount of the spread or more in order to cover the oddsmakers’ runline of -1.5.

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