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Buffalo Bills vs Philadelphia Eagles Predictions, Picks, Odds, and Betting Preview | Nov 26 2023

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After scoring a morale-boosting win in Week 11, the Buffalo Bills will be going for another victory in Week 12 against an elite squad in the form of the Philadelphia Eagles, who have just taken down the reigning Super Bowl champions.

Read on for more about this Bills vs Eagles matchup in the 2023 NFL game, including our predictions, picks, and latest odds to win this showdown, as brought to you by JefeBet. Also, don’t forget to check out other NFL content to help you make the best betting decisions.

Predictions, Odds, and Betting Preview for the Buffalo Bills vs Philadelphia Eagles  NFL Regular Season Week 12 Game on November 26, 2023

  • Where: Lincoln Financial Field, Philadelphia, Pennsylvania
  • When: Sunday, November 26, 2023, 4:25 PM ET
  • Where to Watch: CBS
  • Spread: Buffalo Bills (+3.5) vs Philadelphia Eagles (-3.5)
  • Over/Under: 48.5

All odds are provided by DraftKings.

Betting on the Buffalo Bills (+3.5)

Regular season record: 6-5

The Buffalo Bills prevented a three-game losing skid when they annihilated the New York Jets in Week 11 at home, 32-6. Prior to that, the Bills lost to the Cincinnati Bengals (24-18) on the road and to the Denver Broncos at home in Week 19 (24-22). Josh Allen threw another turnover in the Jets game. 

Still, he had an overall fantastic performance under center, as he had 275 passing yards and three touchdowns with an interception on 20/32 completions. Despite his errors this season, Allen remains one of the better quarterbacks in the league, one who could give the Eagles’ defense a run for its money. As for their defense, the Bills are looking sturdy, with just 17.3 points allowed per game.

Buffalo Bills: +3.5
Philadelphia Eagles: -3.5
* Odds subject to change

Betting on the Philadelphia Eagles (-3.5)

Regular season record: 9-1

The Eagles are flying high. And why wouldn’t they? They just took down the Kansas City Chiefs at Arrowhead Stadium in Week 11, 21-17.  That was also the Eagles’ fourth win in a row, a span that also saw them score wins against the likes of the Dallas Cowboys and the Miami Dolphins. 

The Eagles’ rushing attack and their defense carried Philly against the Chiefs, with D’Andre Swift and Jalen Hurts combining for three touchdowns on the ground. Meanwhile, Philly’s stop unit held Patrick Mahomes to only a 71.7 passer rating and 42.4 quarterback rating. Hurts and the Eagles’ offense could also see some extra possessions against the Bills, who often shoot themselves in the foot with turnovers. The Bills are 25th in the league with 1.7 giveaways per game.

El Jefe’s Prediction on Buffalo Bills vs Philadelphia Eagles

The Eagles thwart the Bills on the strength of Philadelphia’s defense which forces at least two Josh Allen turnovers.


The Eagles win, 24-22.

Bet on the Eagles here


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Written by Barry Recks

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